Thunderstorm allergy

Suddenly, the skin happen to feel itch.

The moisturizer that always use does not fit quickly.

It is said that thunderstorm is one of factor.

So, I examined about that.

Inhaled allergic substance, asthma develop.

Skin is attacked, dermatitis develop.

Asthma and dermatitis are similar.

The literature suggests epidemic thunderstorm asthma occurs due to a complex interaction of patient and environmental factors. Patient factors include previous aeroallergen sensitization and a previous history of allergic rhinitis. Environmental factors include high concentrations of respirable aeroallergens in the atmosphere and thunderstorm outflow tracts that produce downdrafts containing these aeroallergens.

When allergies inhale rapidly and many allergy substance, thunderstorm asthma developed.

I can understand this too.

Impact or thunderstorm shock.

On 21st November 2016, Melbourne experienced an epidemic of ‘thunderstorm asthma.’ Although previously described in the literature, risk factors and natural history remain incompletely understood.

It was said that thunderstorm allergy possibility.

That time, manuals was not make.

Result,an epidemic of thunderstorm asthma in Melbourne.

In Japan, Pollen and dust storm and other many allergic substance existing.

They are carried by the western wind.

Allergic substances are in the world, it can happen any where.

In this study of 263 respondents out of 344 patients presenting to ED with thunderstorm asthma, 58% had no asthma diagnosis. However, 53% of these had a history suggestive of probable undiagnosed asthma. 

58% on thunderstorm asthma had no asthma diagnosis, suddenly asthma developed.

Does thunderstorm asthma always happen?

No, it does not.

By the study in Tasmania, thunderstorm allergy have not happened for five years.

Happening to thunderstorm is not necessarily happen asthma.

Please be careful.

Thunderstorm asthma in Melbourne have fallen for people without diagnosis of asthma.

Even if you think that you do not have allergy.

I want everyone to know "suddenly happen".

If you suddenly feel itchy.

If the moisturizer that always using is not right for you.

It is possibility allergy.

Thank you for reading.

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Citation Paper

An epidemic of thunderstorm asthma in Melbourne 2016: asthma, rhinitis, and other previous allergies

Author : Kanishka B. Rangamuwa, Alan C. Young, and Francis Thien

The Olympics found that Atmospheric Pollution is the cause of asthma.

You may think "Why asthma".

This blog is "itchy column".

The onset of dermatitis and the onset asthma are linked.

Inhaled allergic substance, asthma onset.

Skin attacked, dermatitis onset.

The difference, inhaled or hit.

Air pollution is said that increased allergies.

This time pick up about exhaust fumes, pollen, dust storm.

Air pollution is an alteration of the levels of quality and purity of the air due to natural or anthropogenic emissions of chemical and biological substances.  

Today, tens of thousands of known or suspected air pollutants, sometimes acting in synergy with each other as well as with other parameters (temperature, wind, etc.), are taken into account. 

Air pollution involved not only a substance but also other factors.

First : exhaust fumes

This study is very interesting.

It is not comparison at different place, it is at same place.

The alternative transportation strategy implemented during the 2008 Summer Olympic Games in Beijing (China) provided an opportunity to study the impact of the control measures and weather conditions on air quality and asthma morbidity. The average numbers of outpatient visits for asthma were 12.5 per day at baseline and 7.3 per day during the Olympic events.

This study used Olympic.

A lot of people come there during Olympic season.

Therefore, traffic regulation was done in Beijing.

Result, it is written that asthma patients decreased,and air pollution proved cause of asthma.

Second : pollen

Global warming affects the onset, duration, and intensity of the pollen season as well as the allergenicity of the pollen. Studies on plant responses to elevated atmospheric levels of CO2 indicate that plants exhibit enhanced photosynthesis and reproductive effects and produce more pollen.

Due to global warming, became pollen season longer and intensity of pollen in the air has increase.

Increased CO2 increase pollen too.

There is the data that growth range is widening.

Third : dust storm

Dust storm events were associated with asthma and respiratory admissions to hospitals in many studies. However, the effect varies among published studies. Although many studies have shown a significant increase in asthma exacerbations and hospital admissions, others have shown only mild association with no statistical significance between asthma outcomes and dust storm exposure.

Put it simply, desert storms related to asthma. It can not prove why it happens.

Cause is known in Japan.

Similarly, pollens have been attributed to worsen asthma exacerbations during seasonal dust storms. Watanabe et al., showed worsening asthma symptoms during dust dispersion period, defined as the dust storm day plus the next 6 days in April in Japan, when Japanese cedar pollen levels were increased, which was more common in patients with allergic rhinitis or atopy than in those without.

In Japan, cedar pollen season is February to April, dust storm peak is April.

Ceder pollen season and dust storm peak is same.

Increase asthma patients.

Dust storm and pollen is skin of enemy.

Please be careful.

Ragweed pollen is increase all over the world.



Stop climate change is very hard.

I think that better than myself correspond.

Thank you for reading.

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Citation Paper

Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization

Author:Gennaro D’Amato,Stephen T. Holgate, Ruby Pawankar, Dennis K. Ledford, Lorenzo Cecchi, Mona Al-Ahmad, Fatma Al-Enezi, Saleh Al-Muhsen, Ignacio Ansotegui, Carlos E. Baena-Cagnani, David J. Baker, Hasan Bayram, Karl Christian Bergmann, Louis-Philippe Boulet, Jeroen T. M. Buters, Maria D’Amato, Sofia Dorsano, Jeroen Douwes, Sarah Elise Finlay, Donata Garrasi, Maximiliano Gómez, Tari Haahtela, Rabih Halwani, Youssouf Hassani, Basam Mahboub, Guy Marks, Paola Michelozzi, Marcello Montagni, Carlos Nunes, Jay Jae-Won Oh, Todor A. Popov, Jay Portnoy, Erminia Ridolo, Nelson Rosário, Menachem Rottem, Mario Sánchez-Borges, Elopy Sibanda, Juan José Sienra-Monge, Carolina Vitale, and Isabella Annesi-Maesano

Pollen Allergy, which also destroys the skin

Hello,I am Dr.Ishiguro of itching treatment.

Itchy column but why pollen allergy?

This time is about pollen allergy.

Pollen allergy is also called hay fever and seasonal allergic rhinitis.

Rough skin is one of symptom of pollen allergy.

Pollen Allergy is getting worse every year.

It is not only Japan but also all the world.

Allergic disease is a key public health problem that has increased rapidly in recent decades in both developed and developing countries, and it is now recognized as a major global epidemic.

Pollen are a major cause of symptoms in people with allergic disease.

So pollen allergy is global epidemic.

Major symptom of Pollen Allergy.

1, Rhinitis

2, Asthma

3, Dermatitis

Of course, there are other. These are just "Major" symptom.

Specifically what kind of pollen is the cause of allergy?

In some parts of Europe, ragweed generates ~50% of the total pollen production. In the United States, where ragweed is native, > 26% of the population is sensitized to ragweed.

It is ragweed. Weed native to the United States.

It has spread in Europe.

It will continue to increase in the future.

Why allergic to pollen?

To explain briefly.

Your body recognizes pollen as an enemy.

Rhinitis, asthma, dermatitis.

All these are for getting out or the body.

Eczema causes inflammation and kills the enemy.

It makes me feel itching, and I try to take it off.

So you feel itch.

What should I do?

Pollen makes your body think "not enemy".

Take medicine to reduce inflammation.

Because it's seasonal.

However it is important to start before the season.

Dealing is limited if inflammation occurs.

Before inflammation, you may be able to prevent inflammation.

Important to start before the season.

Thank you for reading.

Citation Paper

Climate Change and Future Pollen Allergy in Europe

Author:Iain R. Lake, Natalia R. Jones, Maureen Agnew, 1 Clare M. Goodess,  Filippo Giorgi, Lynda Hamaoui-Laguel, Mikhail A. Semenov, Fabien Solomon,  Jonathan Storkey,  Robert Vautard, Michelle M. Epstein 

Collagen effect?

We are Miyako-internal-medicine, itchy treatment in Japan.

I write what I studied about itchy.

This theme is collagen!!

What is collagen?

Collagen is substance in the skin, exactly in the dermis.

Skin structure

Collagen decrease when human are older.

Softness and fresh skin will disappear.

So, cover with collagen supplement.

Really cover?

I researched about it.

Collagen effect

I write both effective paper and subtle effect paper.

At first, effective paper

An open-label multicenter study was conducted to investigate the effect of Pure Gold Collagen ingestion on aged skin. 

In total, 217 subjects in arm 1 completed the study. The volunteers were aged 23–69 years and all were Caucasians. All subjects had some photodamage and fine lines/wrinkles. One hundred and fifty-seven subjects had a medium or high distribution of fine lines and/or wrinkles (69 of these subjects agreed that their skin was wrinkled).

Easy summary

217 people drank "pure gold collagen". And it says that it has verified.

157 people had fine lines and wrinkles.

What was the result?

At the end of the study, the dermatologists noted that 109 of these 157 subjects (69%) had either visible or significant improvement in their facial lines (Figure 2A).

157 people had fine lines and wrinkles.

65% of people improved.

Just be careful.

This is not about collagen, about the effect of "pure gold collagen"

It can be said that collagen is effect.

The second, sbtle paper

In this experiment, women in their twenties took drinks containing collagen for 8 weeks, and various measurements were performed.
This experiment was an experiment conducted by a double blind method, and experiments were conducted to obtain objective results as much as possible. There was no significant difference in the moisture content of the skin between the collagen-ingested group and the control group at three time points at the start of the experiment, 4 weeks, and 8 weeks.
However, in the collagen-ingested group, the stratumumabsorption capacity increased statistically significantly after 8 weeks compared with the start of the experiment. Other measurements showed no significant difference, but from this result it is suggested that oral ingestion of collagen improves the moisture retention of the skin.

This is Japanese paper, I translate it into English. (Google Translation)

Easy summary

There was no significant difference in skin moisture content.

Water absorption function increased.

It can be said that collagen reached the skin.

My view

Both of them can not prove that collagen reaches the skin.

Both paper can not prove "Collagen that ate both of them reaches the skin".

So, it is effective for those who think that it is effective.

It is ineffective for those who think it is ineffective.

I think so.

Thank you for reading.

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Citation Paper

Daily consumption of the collagen supplement Pure Gold Collagen® reduces visible signs of aging

Author: Maryam Borumand and Sara Sibilla

コラーゲン経口摂取が結合組織（骨、皮膚）におよぼす作用

Author: Syohei Kasugai,

Sleep and skin aging and itchy

A question to suffering from itching.

"What is trouble?"

Many people said "not sleeping".

It is painful not to sleep.

So, I studied the influence on the skin of luck of sleep.

Various mechanisms have been postulated linking sleep disturbances and eczema, including increases in markers of systemic inflammatory cytokines and T-cell activation. Interleukin-1 induced inflammation is increased in the nighttime which may play a role in enhancing nocturnal itching.

Easy to summarize

"Cytokine itching substances increase at night.

And T-cell and cytokines enhance eczema."


There was a reason to stronger itchy at night.

Of course, many other reasons.

You have something to do in the daytime.

Work, school, playing, etc.

Night have a lot of free time.

Once notice itch it will not be forget, and can not sleep.

What will happen to the skin if you do not sleep?

Poor sleep quality as ascertained by Pittsburgh sleep quality index >5 and sleep duration of ≤5 h was shown to be associated with increased signs of intrinsic aging and decreased skin barrier function when measured by transepidermal water loss.

The moisture of skin decreases and skin barrier function decreases.

Lack of sleep bad the skin.

The sleep deprived individuals were noted to have hanging eyelids, swollen eyes, darker circles and more droopy corners of the mouth.

It also looks bad.And feel bad too.

Lack of sleep is never good thing.

Itching does not give you sleep.

If you do not sleep you will get itchy cytokines.

The skin gets worse and itches.

This said "itch spiral".

"Itching treatment starts with sleep".

Thank you for reading.

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Citation Paper

Overview of Common Sleep Disorders and Intersection with Dermatologic Conditions

Author: Harneet K. Walia and Reena Mehra

About the role of skin : barrier function

About Enemies of the skin

The skin is a highly organized first of defense that stretches up to 1.8㎡, skin is the biggest organ.

Stress of the skin.

For example, factors such as pH, temperature, moisture, sebum level, oxidative stress, diet, resident immune cells, infectious exposure etc.

Conclusion "many!!"

Skin is always attacked, can not rest.

Skin also has several appendages (adena), such as nails, sweat glands, sebaceous glands, and hair follicles, which allow sensation, lubrication, and restriction of heat loss.

Skin is not defensive effect but also sensory organ.

Biggest organ, many enemies, sensory organ.

It is prone to inflammation.

Result It causes itching.

What to do?

The skin has high turnover of cell.

Important thing to use that effect.

Make time for skin to rest.

Skin care is suitable while sleeping.

While sleeping, there are few things that attack the skin such as ultraviolet rays, exhaust gas, and water.

While sleeping, less burdensome to skin.

You can not go to bed because itching.

Suppress itching at that time.

This is the first step in skin care.

Thank you for reading.

Citation Paper

More Than Skin Deep: Autophagy Is Vital for Skin Barrier Function

Author : Payel Sil, Sing-Wai Wong, and Jennifer Martinez

Good skin nutrition

Beautiful skin, it want to be a lot of people.

In fact, me too.

So, searching for something nice way.

I found a paper on nutrition that has good effect on the skin.

The nutrients introduced in this paper

・Vitamins A
Carotenoids are vitamin A derivates like β-carotene, astaxanthin, lycopene and retinol, which are all highly effective antioxidants and have been documented to possess photoprotective properties.

・Vitamins C
Vitamins C also named L-ascorbic acid, is water soluble, photosensitive and is the most important antioxidant in the hydrophilic phase.

・Vitamins D
Also suggest an association between skin aging and levels of 25(OH)D3, another precursor of vitamin D.

・Vitamins E
Vitamin C and vitamin E act synergistically.

・Polyphenols
Polyphenols is mainly because of their antioxidant properties.
Many researches on anti-aging have been announced.

・Ubiquinol (Coenzyme Q10)
Ubiquinol is also a well-known powerful antioxidant compound. In the skin, CoQ10 is mainly to be found in the epidermis where it acts in combination with other enzymic and non-enzymic substances as the initial barrier to oxidant assault.

・Pre - and Probiotics
Clinical studies that used probiotic bacteria (Lactobacillus johnsonii NCC 533) to modulate the cutaneous immune homeostasis altered by solar-simulated UV exposure in humans suggest that certain probiotics can help preserve the skin homeostasis by modulating the skin immune system.

・Essential Fatty Acids (Vitamin F)
Higher linoleic acid intakes were associated with a lower likelihood of senile dryness and skin atrophy.

Is this all nutrients?

This is not everything.

As a reason, all the nutrients have not been found yet.

Not all nutrients such as vegetables, fruits and meats, fishes have been elucidated.

In fact, it is written like in this paper.

"It is effective if you eat fruits and vegetables balanced."

I think so.

It can not be said "This is best !! It's OK"

Let's eat more food than keep eating the same food.

The way I am doing

I try to eat soup that contains a lot of vegetables and meats.

It is easy to cut vegetables and meats and put it in a pot.

Please try!!

Thank you for reading.

Citation Paper

Discovering the link between nutrition and skin aging

Author : Silke K. Schagen,Vasiliki A. Zampeli,  Evgenia Makrantonaki,and Christos C. Zouboulis